SEOUL– South Korean bio firm Sillajen Inc. said Tuesday it is planning to take the first step in testing its licensed new oncology drug.
Three U.S. institutions — the OHSU Knight Cancer Institute, the Mary Crowley Cancer Research and the Montefiore Medical Center — will carry out the phase 1 clinical trial for BAL0891 later this month, the company said.
Sillajen said it is also in talks with Korean hospitals to carry out clinical trials in South Korea.
BAL0891 is a potential first-in-class mitotic checkpoint inhibitor (MCI) that disrupts cell division and leads to tumor cell death.
Sillajen acquired a license for the drug from Switzerland-based Basilea Pharmaceutica International for US$14 million in September.
The company said it found BAL0891 more effective in disrupting cancer cells when taken by injection into a vein than taken by mouth in animal testing. It also demonstrated efficacy when administered with the anti-cancer therapy Paclitaxel, sold under the brand name Taxol.
“We are striving to become a big global pharmaceutical firm by expanding our research and development workforce, and focusing on clinical studies,” Sillajen CEO Kim Jae-kyung said in a press conference. “We will do our best to improve our corporate value.”
The trading of shares in Sillajen resumed on Oct. 13 after 2 1/2 years of suspension over its former executives being charged with embezzlement and breach of trust.
Source: Yonhap News Agency